Application

Research CategoryApoptosis & Cancer

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected LDH-A in human breast cancer sections and human kidney tissue.

Research Sub CategoryApoptosis - Additional

Anti-LDH-A, clone 5D2.1 is an antibody against LDH-A for use in WB, IH.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

L-lactate dehydrogenase A chain (LDHA), also known as Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, and encoded by the gene name LDHA/ PIG19, is a member of the LDH/MDH superfamily and LDH family. Mutations in LDHA have been assoicated with Glycogen storage disease 11 (GSD11), which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.

Immunogen

KLH-conjugated linear peptide corresponding to human LDH-A.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected LDH-A in 10 µg of HeLa cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~37 kDa observed